so...i take neurontin, as well as an ever decreasing amount of seupedol, topomax, and vitamins, b12, magnesium, omegas, ect ect ect

and it's been brought to my attention- that some of these things have very interesting interactions, which my doctor is either unaware of, or just too lazy too inform me of...
i thought i'd share in case any one else is on this combo too.

www.adrugrecall.com/neuronti...ntin.html
www.crazymeds.org/neurontin.html



Neurontin (gabapentin) is basically a neurotransmitter in a pill. Rather, it's
close to the neurotransmitter GABA. GABA can't cross the blood-brain barrier.
True synthesized GABA would have to be injected straight into your noggin. Sorry
to make you cringe. The point is, unlike most psychiatric drugs, what you take
in the capsule (or tablet or oral solution) is what more-or-less what works in
your brain. Neurontin (gabapentin) doesn't need your liver to make what really
does the job. That means it will play well with practically every other
medication there is, right? For us crazies and spazzes, that's right. The only
thing we have to be careful with is stuff like Maalox. As a lot of meds cause
tummy troubles, a lot of us use OTC remedies like Maalox. Maalox interferes a
bit with Neurontin (gabapentin). You just have to wait a couple hours after
taking antacids to take Neurontin (gabapentin).

But people who take Neurontin (gabapentin) for pain, and that includes a lot of
us crazies, as fibromyalgia is far too common in the bipolar community,
Neurontin (gabapentin) has a weird drug-drug interaction with opiates. The
opiates make Neurontin (gabapentin) work better, but the Neurontin (gabapentin)
makes the opiates less efficient! It's weird, and since Neurontin (gabapentin)
isn't really metabolized, who the hell knows what the deal is with that. This is
spelled out in the PI sheet, but who reads those, right? When you take
Neurontin (gabapentin) along with hydrocodone (a.k.a. Vicodin), it decreases the
bioavailability of the hydrocodone by up to 22%! While the bioavailability of
Neurontin (gabapentin) is increased by 14%. It's even odder when combined with
morphine. As Mouse points out there's an element of timing involved, as the
one article on the interaction has morphine administered two hours before the
Neurontin (gabapentin). The morphine was unaffected, having pretty much been
on its way towards peak plasma, but the Neurontin (gabapentin) bioavailability
was increased by a whopping 44%! We have no idea if this effect carries over to
the artificial opiods, like Demerol or buprenorphine.

Meanwhile taking naproxen (a.k.a. Aleve) increases Neurontin's bioavailability
by 12-15%, while there is no apparent affect on naproxen's bioavailability.